Degrade chitin (chitinases)
Bind chitin in the absence of degradation (chitinase-like proteins) to mediate intracellular processes
Genis has developed proprietary chitin derivatives that mimic natural binding partners of the mammalian chitinases and chitinase-like proteins (CLPs), and through them, seek to ameliorate inflammation by deploying innate mechanisms.
In healthy adults, activity of the C/CLP system is stable and highly regulated. However, in a state of inflammation and pathological immunity, expression of these proteins increases significantly.
Prolonged and excessive activation of the C/CLP system can aid in the creation of a destructive environment that can ultimately lead to disease.